Alison Kohan, Ph.D.

Assistant Professor, Department of Nutritional Sciences
University of Connecticut College of Agriculture, Health & Natural Resources

Email: alison.kohan@uconn.edu | Phone: +1 860-486-0866
The Kohan research program focuses on the role of apolipoprotein C-III in mediating cardiovascular disease, and its regulation in the intestine by dietary factors. Major efforts in her research laboratory are focused on: (i) molecular mechanisms of dietary lipid absorption through the gastrointestinal tract, particularly the role of apolipoprotein expression and chylomicron secretion; and (ii) and the influence of plasma lipoproteins, particularly chylomicrons with apoC-III, on metabolic diseases including atherosclerosis and inflammation. Her laboratory has extensive experience in intestinal lipid absorption, lipoprotein synthesis and secretion, plasma lipoprotein metabolism, and more recently she has developed the primary intestinal organoid model for the study of lipoprotein synthesis and secretion. The overall goal of Dr. Kohan’s research is to determine the mechanisms through which intestinal apolipoproteins impact disease in human populations, particularly mtabolic disease and obesity.